# Calibrate

**Type:** Company  
**Domain:** Health  
**Status:** Active  
**Business Model:** Employer-sponsored GLP-1 + behavioral coaching program  
**Market Position:** Premium-tier weight management program ($200-300+/month depending on employer negotiation)  

## Overview

Calibrate operates an employer-sponsored weight management program combining GLP-1 prescriptions with behavioral coaching across four pillars: food, sleep, exercise, and emotional health. The program targets commercially insured, higher-income populations through employer plans.

## Program Structure

- GLP-1 prescriptions
- Coaching on food, sleep, exercise, emotional health (four pillars)
- Regular check-ins and goal tracking
- Weekly weight tracking (80% member engagement)
- Coaching session completion (67% member engagement)

## Key Metrics

**Sample size:** n=17,475 members (Endocrine Society 2025 data)

**Primary outcomes (uninterrupted access):**
- 12-month weight loss: 15.7% average
- 18-month: 17.3%
- 24-month: 17.9% (continued loss, not plateau)
- Waist circumference reduction: avg 6 inches at 12 months

**Interrupted access outcomes:**
- 12-month weight loss: 13.7% (vs. 17% uninterrupted)
- 24-month: 14.9% (vs. 20.1% uninterrupted)
- Delta: ~2.2 percentage points at 12 months; ~5.2 percentage points at 24 months

## Timeline

- **2025-01-01** — Presented interrupted access data at Endocrine Society 2025 showing behavioral coaching creates durability floor: members with treatment interruptions maintained 13.7% weight loss at 12 months vs. standard GLP-1 cessation pattern of ~2/3 weight regain

## Notes

- "Treatment interruptions" criteria not publicly specified
- Endocrine Society presentation not yet peer-reviewed as standalone paper
- No control condition (Calibrate members without behavioral coaching) to isolate behavioral program effect
- Sample entirely employer-sponsored, skewing toward commercially insured, higher-income populations