diff --git a/inbox/queue/.extraction-debug/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.json b/inbox/queue/.extraction-debug/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.json new file mode 100644 index 00000000..8124450a --- /dev/null +++ b/inbox/queue/.extraction-debug/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.json @@ -0,0 +1,24 @@ +{ + "rejected_claims": [ + { + "filename": "llm-copilot-with-rag-architecture-improves-pharmacist-medication-error-detection-by-1-5x-for-serious-harm-cases.md", + "issues": [ + "missing_attribution_extractor" + ] + } + ], + "validation_stats": { + "total": 1, + "kept": 0, + "fixed": 1, + "rejected": 1, + "fixes_applied": [ + "llm-copilot-with-rag-architecture-improves-pharmacist-medication-error-detection-by-1-5x-for-serious-harm-cases.md:set_created:2026-03-24" + ], + "rejections": [ + "llm-copilot-with-rag-architecture-improves-pharmacist-medication-error-detection-by-1-5x-for-serious-harm-cases.md:missing_attribution_extractor" + ] + }, + "model": "anthropic/claude-sonnet-4.5", + "date": "2026-03-24" +} \ No newline at end of file diff --git a/inbox/queue/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.md b/inbox/queue/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.md index af901063..089028e3 100644 --- a/inbox/queue/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.md +++ b/inbox/queue/2025-10-15-cell-reports-medicine-llm-pharmacist-copilot-medication-safety.md @@ -7,9 +7,13 @@ date: 2025-10-15 domain: health secondary_domains: [ai-alignment] format: research-paper -status: unprocessed +status: null-result priority: medium tags: [clinical-ai-safety, centaur-model, medication-safety, llm-copilot, pharmacist, clinical-decision-support, rag, belief-5-counter-evidence] +processed_by: vida +processed_date: 2026-03-24 +extraction_model: "anthropic/claude-sonnet-4.5" +extraction_notes: "LLM returned 1 claims, 1 rejected by validator" --- ## Content @@ -55,3 +59,11 @@ Published in *Cell Reports Medicine*, October 2025 (doi: 10.1016/j.xcrm.2025.003 PRIMARY CONNECTION: Belief 5 counter-evidence — centaur model works under specific conditions WHY ARCHIVED: Best positive clinical AI safety evidence found across 12 sessions; establishes the conditions under which centaur design improves outcomes EXTRACTION HINT: Extract with explicit scope constraint: centaur + RAG + structured safety task = works; general CDSS + automation bias mode = doesn't work per other evidence + + +## Key Facts +- Cell Reports Medicine published prospective cross-over study in October 2025 (doi: 10.1016/j.xcrm.2025.00396-9, PMC12629785) +- Study tested 91 error scenarios based on 40 clinical vignettes across 16 medical and surgical specialties +- Pharmacist + LLM co-pilot achieved 61% accuracy (precision 0.57, recall 0.61, F1 0.59) +- Co-pilot mode increased accuracy by 1.5-fold over pharmacist alone for serious harm errors specifically +- LLM-based CDSS used retrieval-augmented generation (RAG) framework with curated drug database