From e5765c1c17d762bbea83d330ef048a9d3dc52e9c Mon Sep 17 00:00:00 2001 From: Teleo Agents Date: Mon, 13 Apr 2026 04:18:37 +0000 Subject: [PATCH] vida: extract claims from 2026-04-13-calibrate-glp1-behavioral-interrupted-access-outcomes - Source: inbox/queue/2026-04-13-calibrate-glp1-behavioral-interrupted-access-outcomes.md - Domain: health - Claims: 0, Entities: 1 - Enrichments: 1 - Extracted by: pipeline ingest (OpenRouter anthropic/claude-sonnet-4.5) Pentagon-Agent: Vida --- entities/health/calibrate.md | 45 ++++++++++++++++++++++++++++++++++++ 1 file changed, 45 insertions(+) create mode 100644 entities/health/calibrate.md diff --git a/entities/health/calibrate.md b/entities/health/calibrate.md new file mode 100644 index 000000000..08d41b176 --- /dev/null +++ b/entities/health/calibrate.md @@ -0,0 +1,45 @@ +# Calibrate + +**Type:** Company +**Domain:** Health +**Status:** Active +**Business Model:** Employer-sponsored GLP-1 + behavioral coaching program +**Market Position:** Premium-tier weight management program ($200-300+/month depending on employer negotiation) + +## Overview + +Calibrate operates an employer-sponsored weight management program combining GLP-1 prescriptions with behavioral coaching across four pillars: food, sleep, exercise, and emotional health. The program targets commercially insured, higher-income populations through employer plans. + +## Program Structure + +- GLP-1 prescriptions +- Coaching on food, sleep, exercise, emotional health (four pillars) +- Regular check-ins and goal tracking +- Weekly weight tracking (80% member engagement) +- Coaching session completion (67% member engagement) + +## Key Metrics + +**Sample size:** n=17,475 members (Endocrine Society 2025 data) + +**Primary outcomes (uninterrupted access):** +- 12-month weight loss: 15.7% average +- 18-month: 17.3% +- 24-month: 17.9% (continued loss, not plateau) +- Waist circumference reduction: avg 6 inches at 12 months + +**Interrupted access outcomes:** +- 12-month weight loss: 13.7% (vs. 17% uninterrupted) +- 24-month: 14.9% (vs. 20.1% uninterrupted) +- Delta: ~2.2 percentage points at 12 months; ~5.2 percentage points at 24 months + +## Timeline + +- **2025-01-01** — Presented interrupted access data at Endocrine Society 2025 showing behavioral coaching creates durability floor: members with treatment interruptions maintained 13.7% weight loss at 12 months vs. standard GLP-1 cessation pattern of ~2/3 weight regain + +## Notes + +- "Treatment interruptions" criteria not publicly specified +- Endocrine Society presentation not yet peer-reviewed as standalone paper +- No control condition (Calibrate members without behavioral coaching) to isolate behavioral program effect +- Sample entirely employer-sponsored, skewing toward commercially insured, higher-income populations \ No newline at end of file