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_map.md
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AI compresses drug discovery timelines by 30-40 percent but has not yet improved the 90 percent clinical failure rate that determines industry economics.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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AI diagnostic triage achieves 97 percent sensitivity across 14 conditions making AI-first screening viable for all imaging and pathology.md
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AI middleware bridges consumer wearable data to clinical utility because continuous data is too voluminous for direct clinician review.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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AI scribes reached 92 percent provider adoption in under 3 years because documentation is the rare healthcare workflow where AI value is immediate unambiguous and low-risk.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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AI-native health companies achieve 3-5x the revenue productivity of traditional health services because AI eliminates the linear scaling constraint between headcount and output.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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ambient AI documentation reduces physician documentation burden by 73 percent but the relationship between automation and burnout is more complex than time savings alone.md
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ambient-ai-scribes-create-three-party-liability-exposure-outside-fda-oversight.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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ambient-ai-scribes-face-wiretapping-litigation-for-consent-violations.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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Americas declining life expectancy is driven by deaths of despair concentrated in populations and regions most damaged by economic restructuring since the 1980s.md
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auto-fix: strip 11 broken wiki links
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2026-04-01 15:48:32 +00:00 |
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anti-payvidor legislation targets all insurer-provider integration without distinguishing acquisition-based arbitrage from purpose-built care delivery.md
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Big Food companies engineer addictive products by hacking evolutionary reward pathways creating a noncommunicable disease epidemic more deadly than the famines specialization eliminated.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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caregiver-workforce-crisis-shows-all-50-states-experiencing-shortages-with-43-states-reporting-facility-closures-signaling-care-infrastructure-collapse.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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chronic-condition-special-needs-plans-grew-71-percent-in-one-year-indicating-explosive-demand-for-disease-management-infrastructure.md
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clinical-ai-chatbot-misuse-documented-as-top-patient-safety-hazard-two-consecutive-years.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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clinical-ai-hallucination-rates-vary-100x-by-task-making-single-regulatory-thresholds-operationally-inadequate.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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clinical-ai-safety-gap-is-doubly-structural-with-no-pre-deployment-requirements-and-no-post-market-surveillance.md
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fix: strip code fences from Babic MAUDE AI extraction frontmatter
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2026-04-04 11:55:32 +00:00 |
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CMS 2027 chart review exclusion targets vertical integration profit arbitrage by removing upcoded diagnoses from MA risk scoring.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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CMS is creating AI-specific reimbursement codes which will formalize a two-speed adoption system where proven AI applications get payment parity while experimental ones remain in cash-pay limbo.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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consumer CGMs are going mainstream as behavioral change tools not clinical diagnostics because real-time glucose visibility changes food choices even without randomized trial evidence.md
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consumer willingness to pay out of pocket for AI-enhanced care is outpacing reimbursement creating a cash-pay adoption pathway that bypasses traditional payer gatekeeping.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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continuous health monitoring is converging on a multi-layer sensor stack of ambient wearables periodic patches and environmental sensors processed through AI middleware.md
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cvd-mortality-stagnation-affects-all-income-levels-indicating-structural-system-failure.md
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vida: extract claims from 2025-08-01-abrams-aje-pervasive-cvd-stagnation-us-states-counties
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2026-04-04 13:30:05 +00:00 |
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cvd-stagnation-drives-us-life-expectancy-plateau-3-11x-more-than-drug-deaths.md
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vida: extract claims from 2020-03-17-pnas-us-life-expectancy-stalls-cvd-not-drug-deaths
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2026-04-04 13:20:03 +00:00 |
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cvd-stagnation-reversed-racial-health-convergence-by-stopping-black-mortality-improvements.md
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vida: extract claims from 2025-06-01-abrams-brower-cvd-stagnation-black-white-life-expectancy-gap
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2026-04-04 13:27:27 +00:00 |
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Devoted is the fastest-growing MA plan at 121 percent growth because purpose-built technology outperforms acquisition-based vertical integration during CMS tightening.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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enhanced-aca-premium-tax-credit-expiration-creates-second-simultaneous-coverage-loss-pathway-above-medicaid-income-threshold.md
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family-caregiving-functions-as-poverty-transmission-mechanism-forcing-debt-savings-depletion-and-food-insecurity-on-working-age-population.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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famine disease and war are products of the agricultural revolution not immutable features of human existence and specialization has converted all three from unforeseeable catastrophes into preventable problems.md
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FDA is replacing animal testing with AI models and organ-on-chip as the default preclinical pathway which will compress drug development timelines and reduce the 90 percent clinical failure rate.md
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fda-2026-cds-enforcement-discretion-expands-to-single-recommendation-ai-without-defining-clinical-appropriateness.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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fda-maude-cannot-identify-ai-contributions-to-adverse-events-due-to-structural-reporting-gaps.md
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vida: extract claims from 2024-xx-handley-npj-ai-safety-issues-fda-device-reports
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2026-04-02 10:46:33 +00:00 |
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fda-maude-database-lacks-ai-specific-adverse-event-fields-creating-systematic-under-detection-of-ai-attributable-harm.md
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fix: strip code fences from Babic MAUDE AI extraction frontmatter
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2026-04-04 11:55:32 +00:00 |
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fda-transparency-requirements-treat-clinician-understanding-as-sufficient-oversight-despite-automation-bias-evidence.md
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vida: extract claims from 2026-01-06-fda-cds-software-deregulation-ai-wearables-guidance
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2026-04-04 13:39:37 +00:00 |
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fda-treats-automation-bias-as-transparency-problem-contradicting-evidence-that-visibility-does-not-prevent-deference.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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federal-budget-scoring-methodology-systematically-undervalues-preventive-interventions-because-10-year-window-excludes-long-term-savings.md
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five-adverse-sdoh-independently-predict-hypertension-risk-food-insecurity-unemployment-poverty-low-education-inadequate-insurance.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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food-as-medicine-interventions-produce-clinically-significant-improvements-during-active-delivery-but-benefits-fully-revert-when-structural-food-environment-support-is-removed.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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food-insecurity-creates-bidirectional-reinforcing-loop-with-cvd-through-medical-costs-and-dietary-quality.md
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vida: extract claims from 2025-01-xx-bmc-food-insecurity-cvd-risk-factors-us-adults
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2026-04-04 13:26:24 +00:00 |
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food-insecurity-independently-predicts-41-percent-higher-cvd-incidence-establishing-temporality-for-sdoh-cardiovascular-pathway.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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four competing payer-provider models are converging toward value-based care with vertical integration dominant today but aligned partnership potentially more durable.md
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Function Health drives down diagnostic conversion costs to 499 per year for 100-plus lab tests making atoms-to-bits health data generation accessible at consumer scale.md
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gatekeeping-systems-optimize-primary-care-at-the-expense-of-specialty-access-creating-structural-bottlenecks.md
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gene editing is shifting from ex vivo to in vivo delivery via lipid nanoparticles which will reduce curative therapy costs from millions to hundreds of thousands per treatment.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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generative-ai-medical-devices-require-new-regulatory-frameworks-because-non-determinism-continuous-updates-and-inherent-hallucination-are-architectural-properties.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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generic-digital-health-deployment-reproduces-existing-disparities-by-disproportionately-benefiting-higher-income-users-despite-nominal-technology-access-equity.md
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extract: 2024-09-xx-pmc-equity-digital-health-rpm-wearables-underserved-communities
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2026-03-31 04:32:01 +00:00 |
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GLP-1 cost evidence accelerates value-based care adoption by proving that prevention-first interventions generate net savings under capitation within 24 months.md
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vida: add GLP-1→VBC cross-domain claim + provider consolidation musing
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2026-04-03 20:24:09 +00:00 |
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GLP-1 receptor agonists are the largest therapeutic category launch in pharmaceutical history but their chronic use model makes the net cost impact inflationary through 2035.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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glp-1-access-structure-inverts-need-creating-equity-paradox.md
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vida: extract claims from 2026-02-01-lancet-making-obesity-treatment-more-equitable
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2026-04-03 14:18:24 +00:00 |
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glp-1-multi-organ-protection-creates-compounding-value-across-kidney-cardiovascular-and-metabolic-endpoints.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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glp-1-persistence-drops-to-15-percent-at-two-years-for-non-diabetic-obesity-patients-undermining-chronic-use-economics.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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glp-1-population-mortality-impact-delayed-20-years-by-access-and-adherence-constraints.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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glp1-access-inverted-by-cardiovascular-risk-creating-efficacy-translation-barrier.md
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entity-batch: update 1 entities
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2026-04-03 14:22:08 +00:00 |
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healthcare AI creates a Jevons paradox because adding capacity to sick care induces more demand for sick care.md
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vida: add supports link from healthcare Jevons claim to fragility-from-efficiency foundation
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2026-04-03 20:24:10 +00:00 |
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healthcare AI funding follows a winner-take-most pattern with category leaders absorbing capital at unprecedented velocity while 35 percent of deals are flat or down rounds.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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healthcare AI regulation needs blank-sheet redesign because the FDA drug-and-device model built for static products cannot govern continuously learning software.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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healthcare is a complex adaptive system requiring simple enabling rules not complicated management because standardized processes erode the clinical autonomy needed for value creation.md
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healthcares defensible layer is where atoms become bits because physical-to-digital conversion generates the data that powers AI care while building patient trust that software alone cannot create.md
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home-based-care-could-capture-265-billion-in-medicare-spending-by-2025-through-hospital-at-home-remote-monitoring-and-post-acute-shift.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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human-in-the-loop clinical AI degrades to worse-than-AI-alone because physicians both de-skill from reliance and introduce errors when overriding correct outputs.md
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hypertension-related-cvd-mortality-doubled-2000-2023-despite-available-treatment-indicating-behavioral-sdoh-failure.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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hypertensive-disease-mortality-doubled-1999-2023-becoming-leading-contributing-cvd-cause.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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japan-demographic-trajectory-provides-20-year-preview-of-us-long-term-care-challenge.md
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japan-ltci-proves-mandatory-universal-long-term-care-insurance-is-viable-at-national-scale.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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Kaiser Permanentes 80-year tripartite structure is the strongest precedent for purpose-built payvidor exemptions because any structural separation bill that captures Kaiser faces 12.5 million members and Californias entire healthcare infrastructure.md
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llm-nursing-care-plans-exhibit-dual-pathway-sociodemographic-bias-in-content-and-expert-rated-quality.md
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vida: extract claims from 2025-01-01-jmir-e78132-llm-nursing-care-plan-sociodemographic-bias
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2026-04-04 13:25:20 +00:00 |
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lower-income-patients-show-higher-glp-1-discontinuation-rates-suggesting-affordability-not-just-clinical-factors-drive-persistence.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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medical care explains only 10-20 percent of health outcomes because behavioral social and genetic factors dominate as four independent methodologies confirm.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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medical LLM benchmark performance does not translate to clinical impact because physicians with and without AI access achieve similar diagnostic accuracy in randomized trials.md
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medically-tailored-meals-achieve-pharmacotherapy-scale-bp-reduction-in-food-insecure-hypertensive-patients.md
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vida: extract claims from 2025-07-09-medrxiv-kentucky-mtm-grocery-prescription-bp-reduction-9mmhg
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2026-04-01 16:38:15 +00:00 |
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medicare-advantage-crossed-majority-enrollment-in-2023-marking-structural-transformation-from-supplement-to-dominant-program.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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medicare-advantage-market-is-an-oligopoly-with-unitedhealthgroup-and-humana-controlling-46-percent-despite-nominal-plan-choice.md
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medicare-advantage-spending-gap-grew-47x-while-enrollment-doubled-indicating-scale-worsens-overpayment-problem.md
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medicare-fiscal-pressure-forces-ma-reform-by-2030s-through-arithmetic-not-ideology.md
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medicare-trust-fund-insolvency-accelerated-12-years-by-tax-policy-demonstrating-fiscal-fragility.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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midlife-cvd-mortality-increased-in-many-us-states-after-2010-representing-reversal-not-stagnation.md
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vida: extract claims from 2025-08-01-abrams-aje-pervasive-cvd-stagnation-us-states-counties
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2026-04-04 13:30:05 +00:00 |
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modernization dismantles family and community structures replacing them with market and state relationships that increase individual freedom but erode psychosocial foundations of wellbeing.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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nhs-demonstrates-universal-coverage-without-adequate-funding-produces-excellent-primary-care-but-catastrophic-specialty-access.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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no-regulatory-body-globally-has-established-mandatory-hallucination-rate-benchmarks-for-clinical-ai-despite-evidence-base.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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only-23-percent-of-treated-us-hypertensives-achieve-blood-pressure-control-demonstrating-pharmacological-availability-is-not-the-binding-constraint.md
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extract: 2026-01-21-aha-2026-heart-disease-stroke-statistics-update
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2026-04-03 14:17:16 +00:00 |
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OpenEvidence became the fastest-adopted clinical technology in history reaching 40 percent of US physicians daily within two years.md
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Oura controls 80 percent of the smart ring market with patent-defended form factor while a demographic pivot from fitness enthusiasts to wellness-focused women drives 250 percent sales growth.md
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pace-demonstrates-integrated-care-averts-institutionalization-through-community-based-delivery-not-cost-reduction.md
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pace-restructures-costs-from-acute-to-chronic-spending-without-reducing-total-expenditure-challenging-prevention-saves-money-narrative.md
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pcsk9-inhibitors-achieved-only-1-to-2-5-percent-penetration-despite-proven-efficacy-demonstrating-access-mediated-pharmacological-ceiling.md
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extract: 2026-03-30-jacc-cvd-mortality-trends-1999-2023
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2026-03-30 05:46:23 +00:00 |
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personalized mRNA cancer vaccines show sustained 49 percent reduction in melanoma recurrence after five years representing a genuinely novel therapeutic paradigm.md
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prescription digital therapeutics failed as a business model because FDA clearance creates regulatory cost without the pricing power that justifies it for near-zero marginal cost software.md
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racial-disparities-in-hypertension-persist-after-controlling-for-income-and-neighborhood-indicating-structural-racism-operates-through-unmeasured-mechanisms.md
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extract: 2024-06-xx-aha-hypertension-sdoh-systematic-review-57-studies
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2026-03-31 11:31:04 +00:00 |
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regulatory-deregulation-occurring-during-active-harm-accumulation-not-after-safety-evidence.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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rpm-technology-stack-enables-facility-to-home-care-migration-through-ai-middleware-that-converts-continuous-data-into-clinical-utility.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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rural-food-insecure-populations-show-higher-enrollment-in-food-assistance-interventions-than-urban-counterparts.md
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vida: extract claims from 2025-07-09-medrxiv-kentucky-mtm-grocery-prescription-bp-reduction-9mmhg
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2026-04-01 16:38:15 +00:00 |
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SDOH interventions show strong ROI but adoption stalls because Z-code documentation remains below 3 percent and no operational infrastructure connects screening to action.md
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auto-fix: strip 11 broken wiki links
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2026-04-01 15:48:32 +00:00 |
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semaglutide-achieves-47-percent-one-year-persistence-versus-19-percent-for-liraglutide-showing-drug-specific-adherence-variation-of-2-5x.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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semaglutide-cardiovascular-benefit-is-67-percent-independent-of-weight-loss-with-inflammation-as-primary-mediator.md
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entity-batch: update 1 entities
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2026-03-30 12:45:54 +00:00 |
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semaglutide-reduces-kidney-disease-progression-24-percent-and-delays-dialysis-creating-largest-per-patient-cost-savings.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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snap-benefit-loss-causes-measurable-mortality-through-food-insecurity-pathway.md
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vida: extract claims from 2025-xx-penn-ldi-obbba-snap-cuts-93000-premature-deaths
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2026-04-01 16:37:34 +00:00 |
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snap-reduces-antihypertensive-nonadherence-through-food-medication-trade-off-relief.md
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vida: extract claims from 2024-02-23-jama-network-open-snap-antihypertensive-adherence-food-insecure
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2026-04-01 16:37:39 +00:00 |
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social isolation costs Medicare 7 billion annually and carries mortality risk equivalent to smoking 15 cigarettes per day making loneliness a clinical condition not a personal problem.md
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state-clinical-ai-disclosure-laws-fill-federal-regulatory-gap-created-by-fda-enforcement-discretion-expansion.md
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vida: extract claims from 2025-10-xx-california-ab489-ai-healthcare-disclosure-2026
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2026-04-03 14:24:56 +00:00 |
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tailored-digital-health-interventions-achieve-sustained-bp-reduction-in-disparity-populations-but-effect-requires-population-specific-design.md
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vida: extract claims from 2024-02-05-jama-network-open-digital-health-hypertension-disparities-meta-analysis
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2026-04-04 13:21:09 +00:00 |
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tempo-pilot-creates-medicare-digital-health-pathway-while-medicaid-coverage-contracts.md
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extract: 2026-04-01-fda-tempo-cms-access-selection-pending-july-performance-period
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2026-04-01 16:07:12 +00:00 |
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the epidemiological transition marks the shift from material scarcity to social disadvantage as the primary driver of health outcomes in developed nations.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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the FDA now separates wellness devices from medical devices based on claims not sensor technology enabling health insights without full medical device classification.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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the healthcare attractor state is a prevention-first system where aligned payment continuous monitoring and AI-augmented care delivery create a flywheel that profits from health rather than sickness.md
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the healthcare cost curve bends up through 2035 because new curative and screening capabilities create more treatable conditions faster than prices decline.md
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the mental health supply gap is widening not closing because demand outpaces workforce growth and technology primarily serves the already-served rather than expanding access.md
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reweave: connect 39 orphan claims via vector similarity
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2026-04-03 14:01:58 +00:00 |
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the physician role shifts from information processor to relationship manager as AI automates documentation triage and evidence synthesis.md
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ultra-processed-food-consumption-increases-incident-hypertension-through-chronic-inflammation-pathway.md
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vida: extract claims from 2024-10-xx-aha-regards-upf-hypertension-cohort-9-year-followup
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2026-04-04 13:23:13 +00:00 |
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unpaid-family-caregiving-provides-870-billion-annually-representing-16-percent-of-total-us-health-economy-invisible-to-policy-models.md
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reweave: connect 48 orphan claims via vector similarity
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2026-03-28 23:04:53 +00:00 |
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upf-driven-chronic-inflammation-creates-continuous-vascular-risk-regeneration-explaining-antihypertensive-treatment-failure.md
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vida: extract claims from 2024-10-xx-aha-regards-upf-hypertension-cohort-9-year-followup
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2026-04-04 13:23:13 +00:00 |
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us-cvd-mortality-bifurcating-ischemic-declining-heart-failure-hypertension-worsening.md
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extract: 2026-01-21-aha-2026-heart-disease-stroke-statistics-update
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2026-04-03 14:17:16 +00:00 |
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us-healthcare-ranks-last-among-peer-nations-despite-highest-spending-because-access-and-equity-failures-override-clinical-quality.md
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us-healthspan-declining-while-lifespan-recovers-creating-divergence.md
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vida: extract claims from 2024-12-02-jama-network-open-global-healthspan-lifespan-gaps-183-who-states
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2026-04-04 13:24:16 +00:00 |
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us-healthspan-lifespan-gap-largest-globally-despite-highest-spending.md
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vida: extract claims from 2024-12-02-jama-network-open-global-healthspan-lifespan-gaps-183-who-states
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2026-04-04 13:24:16 +00:00 |
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us-heart-failure-mortality-reversed-1999-2023-exceeding-baseline-despite-acute-care-improvements.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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us-long-term-care-financing-gap-is-largest-unaddressed-structural-problem-in-american-healthcare.md
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reweave: connect 29 orphan claims via vector similarity
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2026-03-31 10:50:34 +00:00 |
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value-based care transitions stall at the payment boundary because 60 percent of payments touch value metrics but only 14 percent bear full risk.md
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reweave: connect 31 orphan claims via vector similarity (manual apply of PR #2313)
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2026-04-04 12:30:11 +00:00 |
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WHOOP subscription-only wearable model generates $260M revenue but trails Oura at half the revenue and a third the valuation because fitness-first positioning limits the addressable wellness market.md
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