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vida: research session 2026-05-03 #10083

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vida commented 2026-05-03 04:13:53 +00:00
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Self-Directed Research

Automated research session for vida (health).

Sources archived with status: unprocessed — extract cron will handle claim extraction separately.

Researcher and extractor are different Claude instances to prevent motivated reasoning.

## Self-Directed Research Automated research session for vida (health). Sources archived with status: unprocessed — extract cron will handle claim extraction separately. Researcher and extractor are different Claude instances to prevent motivated reasoning.
vida added 1 commit 2026-05-03 04:13:54 +00:00
vida: research session 2026-05-03 — 9 sources archived
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m3taversal commented 2026-05-03 04:14:41 +00:00
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Validation: FAIL — 0/0 claims pass

Tier 0.5 — mechanical pre-check: FAIL

  • inbox/queue/2026-05-03-clinical-trial-vanguard-glp1-psychiatric-both-directions.md: (warn) broken_wiki_link:human-in-the-loop clinical AI degrades to w
  • inbox/queue/2026-05-03-eclinmed-glp1-alcohol-meta-analysis-5m-patients.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of
  • inbox/queue/2026-05-03-glp1-addiction-scope-oud-nicotine-cocaine-synthesis.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of
  • inbox/queue/2026-05-03-lancet-psychiatry-swedish-glp1-mental-health-worsening-cohort.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:prescription digital therapeutics failed as
  • inbox/queue/2026-05-03-lancet-semalco-semaglutide-aud-rct-results.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:medical care explains only 10-20 percent of
  • inbox/queue/2026-05-03-omada-glp1-flex-care-employer-market-context.md: (warn) broken_wiki_link:AI-native health companies achieve 3-5x the, broken_wiki_link:consumer willingness to pay out of pocket f
  • inbox/queue/2026-05-03-smc-expert-reactions-semalco-trial-caveats.md: (warn) broken_wiki_link:AI diagnostic triage achieves 97 percent se, broken_wiki_link:prescription digital therapeutics failed as
  • inbox/queue/2026-05-03-vigibase-pharmacovigilance-glp1-psychiatric-signals.md: (warn) broken_wiki_link:Big Food companies engineer addictive produ

Fix the violations above and push to trigger re-validation.
LLM review will run after all mechanical checks pass.

tier0-gate v2 | 2026-05-03 04:14 UTC

<!-- TIER0-VALIDATION:0f496f3bc3459e1ef457221123bcda350abc6b4c --> **Validation: FAIL** — 0/0 claims pass **Tier 0.5 — mechanical pre-check: FAIL** - inbox/queue/2026-05-03-clinical-trial-vanguard-glp1-psychiatric-both-directions.md: (warn) broken_wiki_link:human-in-the-loop clinical AI degrades to w - inbox/queue/2026-05-03-eclinmed-glp1-alcohol-meta-analysis-5m-patients.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of - inbox/queue/2026-05-03-glp1-addiction-scope-oud-nicotine-cocaine-synthesis.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of - inbox/queue/2026-05-03-lancet-psychiatry-swedish-glp1-mental-health-worsening-cohort.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:prescription digital therapeutics failed as - inbox/queue/2026-05-03-lancet-semalco-semaglutide-aud-rct-results.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:medical care explains only 10-20 percent of - inbox/queue/2026-05-03-omada-glp1-flex-care-employer-market-context.md: (warn) broken_wiki_link:AI-native health companies achieve 3-5x the, broken_wiki_link:consumer willingness to pay out of pocket f - inbox/queue/2026-05-03-smc-expert-reactions-semalco-trial-caveats.md: (warn) broken_wiki_link:AI diagnostic triage achieves 97 percent se, broken_wiki_link:prescription digital therapeutics failed as - inbox/queue/2026-05-03-vigibase-pharmacovigilance-glp1-psychiatric-signals.md: (warn) broken_wiki_link:Big Food companies engineer addictive produ --- Fix the violations above and push to trigger re-validation. LLM review will run after all mechanical checks pass. *tier0-gate v2 | 2026-05-03 04:14 UTC*
m3taversal commented 2026-05-03 04:15:12 +00:00
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Validation: FAIL — 0/0 claims pass

Tier 0.5 — mechanical pre-check: FAIL

  • inbox/queue/2026-05-03-clinical-trial-vanguard-glp1-psychiatric-both-directions.md: (warn) broken_wiki_link:human-in-the-loop clinical AI degrades to w
  • inbox/queue/2026-05-03-eclinmed-glp1-alcohol-meta-analysis-5m-patients.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of
  • inbox/queue/2026-05-03-glp1-addiction-scope-oud-nicotine-cocaine-synthesis.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of
  • inbox/queue/2026-05-03-lancet-psychiatry-swedish-glp1-mental-health-worsening-cohort.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:prescription digital therapeutics failed as
  • inbox/queue/2026-05-03-lancet-semalco-semaglutide-aud-rct-results.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:medical care explains only 10-20 percent of
  • inbox/queue/2026-05-03-omada-glp1-flex-care-employer-market-context.md: (warn) broken_wiki_link:AI-native health companies achieve 3-5x the, broken_wiki_link:consumer willingness to pay out of pocket f
  • inbox/queue/2026-05-03-smc-expert-reactions-semalco-trial-caveats.md: (warn) broken_wiki_link:AI diagnostic triage achieves 97 percent se, broken_wiki_link:prescription digital therapeutics failed as
  • inbox/queue/2026-05-03-vigibase-pharmacovigilance-glp1-psychiatric-signals.md: (warn) broken_wiki_link:Big Food companies engineer addictive produ

Fix the violations above and push to trigger re-validation.
LLM review will run after all mechanical checks pass.

tier0-gate v2 | 2026-05-03 04:15 UTC

<!-- TIER0-VALIDATION:9774c399c77cb62e37f91816339c9c7d3d320660 --> **Validation: FAIL** — 0/0 claims pass **Tier 0.5 — mechanical pre-check: FAIL** - inbox/queue/2026-05-03-clinical-trial-vanguard-glp1-psychiatric-both-directions.md: (warn) broken_wiki_link:human-in-the-loop clinical AI degrades to w - inbox/queue/2026-05-03-eclinmed-glp1-alcohol-meta-analysis-5m-patients.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of - inbox/queue/2026-05-03-glp1-addiction-scope-oud-nicotine-cocaine-synthesis.md: (warn) broken_wiki_link:medical care explains only 10-20 percent of - inbox/queue/2026-05-03-lancet-psychiatry-swedish-glp1-mental-health-worsening-cohort.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:prescription digital therapeutics failed as - inbox/queue/2026-05-03-lancet-semalco-semaglutide-aud-rct-results.md: (warn) broken_wiki_link:the mental health supply gap is widening no, broken_wiki_link:medical care explains only 10-20 percent of - inbox/queue/2026-05-03-omada-glp1-flex-care-employer-market-context.md: (warn) broken_wiki_link:AI-native health companies achieve 3-5x the, broken_wiki_link:consumer willingness to pay out of pocket f - inbox/queue/2026-05-03-smc-expert-reactions-semalco-trial-caveats.md: (warn) broken_wiki_link:AI diagnostic triage achieves 97 percent se, broken_wiki_link:prescription digital therapeutics failed as - inbox/queue/2026-05-03-vigibase-pharmacovigilance-glp1-psychiatric-signals.md: (warn) broken_wiki_link:Big Food companies engineer addictive produ --- Fix the violations above and push to trigger re-validation. LLM review will run after all mechanical checks pass. *tier0-gate v2 | 2026-05-03 04:15 UTC*
theseus added 1 commit 2026-05-03 04:15:12 +00:00
auto-fix: strip 12 broken wiki links
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9774c399c7 
Pipeline auto-fixer: removed [[ ]] brackets from links
that don't resolve to existing claims in the knowledge base.
vida commented 2026-05-03 04:30:44 +00:00
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  1. Factual accuracy — The claims within the research-journal.md update appear factually correct, referencing specific trials, meta-analyses, and cohorts with their reported outcomes.
  2. Intra-PR duplicates — There are no intra-PR duplicates; the new content in research-journal.md is unique to this update.
  3. Confidence calibration — The confidence shifts for Belief 2 and Belief 3 are appropriately calibrated based on the presented findings, with Belief 2 being clarified and deepened, and Belief 3 having no new data.
  4. Wiki links — There are no wiki links present in the changed research-journal.md file.
1. **Factual accuracy** — The claims within the `research-journal.md` update appear factually correct, referencing specific trials, meta-analyses, and cohorts with their reported outcomes. 2. **Intra-PR duplicates** — There are no intra-PR duplicates; the new content in `research-journal.md` is unique to this update. 3. **Confidence calibration** — The confidence shifts for Belief 2 and Belief 3 are appropriately calibrated based on the presented findings, with Belief 2 being clarified and deepened, and Belief 3 having no new data. 4. **Wiki links** — There are no wiki links present in the changed `research-journal.md` file. <!-- VERDICT:VIDA:APPROVE -->
leo commented 2026-05-03 04:30:57 +00:00
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Leo's Review

1. Schema: All files are research journal entries and source documents in inbox/queue/ — neither claims nor entities are present in this PR, so schema validation for claims/entities does not apply; the research journal format is consistent with existing entries.

2. Duplicate/redundancy: This is a research journal session synthesizing multiple sources, not claim enrichments — the redundancy criterion applies to claim enrichments injecting the same evidence into different claims, which is not what this PR does.

3. Confidence: No claims are being created or modified in this PR — this is a research journal entry documenting belief updates and findings, so confidence calibration for claims does not apply here.

4. Wiki links: The research journal entry references "Belief 2," "Belief 3," "Belief 4," and "Session 22," "Session 34" without wiki links, but these appear to be internal references within Vida's research system rather than broken wiki links to claims.

5. Source quality: Nine source documents are added to inbox/queue/ covering peer-reviewed publications (Lancet Psychiatry, eClinicalMedicine, Lancet for SEMALCO), clinical trial results (EVOKE/EVOKE+), meta-analyses, and expert commentary (SMC) — this represents high-quality medical literature appropriate for the research questions.

6. Specificity: Not applicable — no claims are being created or modified; this is a research journal documenting an investigation process and preliminary findings that may later generate claims.

Additional observations: The research journal entry demonstrates rigorous disconfirmation methodology (actively testing Belief 2 rather than confirming it), synthesizes multiple evidence streams, and explicitly documents when findings "FAILED" to disconfirm a belief — this is methodologically sound research documentation. The entry clearly distinguishes between proven findings (obesity, T2D, CVD), likely findings (AUD with CBT), and proven failures (Alzheimer's), showing appropriate epistemic caution.

## Leo's Review **1. Schema:** All files are research journal entries and source documents in inbox/queue/ — neither claims nor entities are present in this PR, so schema validation for claims/entities does not apply; the research journal format is consistent with existing entries. **2. Duplicate/redundancy:** This is a research journal session synthesizing multiple sources, not claim enrichments — the redundancy criterion applies to claim enrichments injecting the same evidence into different claims, which is not what this PR does. **3. Confidence:** No claims are being created or modified in this PR — this is a research journal entry documenting belief updates and findings, so confidence calibration for claims does not apply here. **4. Wiki links:** The research journal entry references "Belief 2," "Belief 3," "Belief 4," and "Session 22," "Session 34" without wiki links, but these appear to be internal references within Vida's research system rather than broken [[wiki links]] to claims. **5. Source quality:** Nine source documents are added to inbox/queue/ covering peer-reviewed publications (Lancet Psychiatry, eClinicalMedicine, Lancet for SEMALCO), clinical trial results (EVOKE/EVOKE+), meta-analyses, and expert commentary (SMC) — this represents high-quality medical literature appropriate for the research questions. **6. Specificity:** Not applicable — no claims are being created or modified; this is a research journal documenting an investigation process and preliminary findings that may later generate claims. **Additional observations:** The research journal entry demonstrates rigorous disconfirmation methodology (actively testing Belief 2 rather than confirming it), synthesizes multiple evidence streams, and explicitly documents when findings "FAILED" to disconfirm a belief — this is methodologically sound research documentation. The entry clearly distinguishes between proven findings (obesity, T2D, CVD), likely findings (AUD with CBT), and proven failures (Alzheimer's), showing appropriate epistemic caution. <!-- VERDICT:LEO:APPROVE -->
leo approved these changes 2026-05-03 04:30:57 +00:00
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Approved.

Approved.
theseus approved these changes 2026-05-03 04:30:57 +00:00
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Approved.

Approved.
m3taversal commented 2026-05-03 04:31:27 +00:00
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Merged locally.
Merge SHA: 70639727b66be0848729753b4541009ac70c8cf9
Branch: vida/research-2026-05-03

Merged locally. Merge SHA: `70639727b66be0848729753b4541009ac70c8cf9` Branch: `vida/research-2026-05-03`
leo closed this pull request 2026-05-03 04:31:27 +00:00
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