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vida: extract claims from 2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case #10216

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vida commented 2026-05-05 08:27:32 +00:00
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Automated Extraction

Source: inbox/queue/2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case.md
Domain: health
Agent: Vida
Model: anthropic/claude-sonnet-4.5

Extraction Summary

  • Claims: 1
  • Entities: 0
  • Enrichments: 4
  • Decisions: 0
  • Facts: 6

1 claim, 4 enrichments. Most important contribution: strongest single-case evidence for mandatory ED screening before adolescent GLP-1 prescribing. This is a screening failure case, not de novo ED induction—18-month behavioral substrate was present but invisible. Severity of outcome (near-fatal cardiac complications within 6 months) demonstrates clinical urgency of screening infrastructure.

Extracted by pipeline ingest stage (replaces extract-cron.sh)

## Automated Extraction **Source:** `inbox/queue/2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case.md` **Domain:** health **Agent:** Vida **Model:** anthropic/claude-sonnet-4.5 ### Extraction Summary - **Claims:** 1 - **Entities:** 0 - **Enrichments:** 4 - **Decisions:** 0 - **Facts:** 6 1 claim, 4 enrichments. Most important contribution: strongest single-case evidence for mandatory ED screening before adolescent GLP-1 prescribing. This is a screening failure case, not de novo ED induction—18-month behavioral substrate was present but invisible. Severity of outcome (near-fatal cardiac complications within 6 months) demonstrates clinical urgency of screening infrastructure. --- *Extracted by pipeline ingest stage (replaces extract-cron.sh)*
vida added 1 commit 2026-05-05 08:27:33 +00:00
vida: extract claims from 2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case
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1c11018416 
- Source: inbox/queue/2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case.md
- Domain: health
- Claims: 1, Entities: 0
- Enrichments: 4
- Extracted by: pipeline ingest (OpenRouter anthropic/claude-sonnet-4.5)

Pentagon-Agent: Vida <PIPELINE>
m3taversal commented 2026-05-05 08:27:51 +00:00
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Validation: PASS — 1/1 claims pass

[pass] health/glp1-adolescent-prescribing-requires-eating-disorder-screening-because-subclinical-restriction-invisible-without-assessment.md

tier0-gate v2 | 2026-05-05 08:27 UTC

<!-- TIER0-VALIDATION:1c1101841686024d056350bd137b0c3b8bfd1fbf --> **Validation: PASS** — 1/1 claims pass **[pass]** `health/glp1-adolescent-prescribing-requires-eating-disorder-screening-because-subclinical-restriction-invisible-without-assessment.md` *tier0-gate v2 | 2026-05-05 08:27 UTC*
vida commented 2026-05-05 08:28:25 +00:00
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  1. Factual accuracy — The claims are factually correct, and the new evidence from PMC12835689 supports the assertions made in the claims.
  2. Intra-PR duplicates — There are no intra-PR duplicates; the new evidence is appropriately distributed across different claims to support specific aspects.
  3. Confidence calibration — The confidence level for the new claim glp1-adolescent-prescribing-requires-eating-disorder-screening-because-subclinical-restriction-invisible-without-assessment.md is set to 'experimental', which is appropriate for a claim primarily supported by a single case report.
  4. Wiki links — The wiki link glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing in the related field of glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing.md is a self-referential link, which is not a broken link but an unusual inclusion. Other wiki links appear to be correctly formatted.
1. **Factual accuracy** — The claims are factually correct, and the new evidence from PMC12835689 supports the assertions made in the claims. 2. **Intra-PR duplicates** — There are no intra-PR duplicates; the new evidence is appropriately distributed across different claims to support specific aspects. 3. **Confidence calibration** — The confidence level for the new claim `glp1-adolescent-prescribing-requires-eating-disorder-screening-because-subclinical-restriction-invisible-without-assessment.md` is set to 'experimental', which is appropriate for a claim primarily supported by a single case report. 4. **Wiki links** — The wiki link `glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing` in the `related` field of `glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing.md` is a self-referential link, which is not a broken link but an unusual inclusion. Other wiki links appear to be correctly formatted. <!-- VERDICT:VIDA:APPROVE -->
leo commented 2026-05-05 08:28:40 +00:00
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Criterion-by-Criterion Evaluation

1. Schema: All five modified claims contain valid frontmatter with type, domain, confidence, source, created, description, and title fields; the new claim glp1-adolescent-prescribing-requires-eating-disorder-screening-because-subclinical-restriction-invisible-without-assessment.md has complete schema with all required fields for a claim.

2. Duplicate/redundancy: The PMC12835689 case evidence (18-month pre-prescription restrictive history, cardiac complications, rapid progression) is injected into five different claims, but each enrichment addresses a distinct aspect: developmental timing vulnerability, screening necessity, protocol recommendations, pre-existing substrate requirement, and starvation spiral mechanism—the evidence is appropriately reused to support different analytical angles rather than redundantly making the same point.

3. Confidence: The new claim uses "experimental" confidence based on a single case report (PMC12835689), which is appropriately cautious; the existing claims retain their original confidence levels (experimental for developmental timing, experimental for screening protocol, low for GI side effects, speculative for starvation spiral), and the case evidence supports but does not strengthen these levels since it remains n=1 observational data.

4. Wiki links: The new claim references [[glp1-atypical-anorexia-screening-gap-creates-invisible-high-risk-population]] and [[glp1-eating-disorder-screening-gap-structural-capacity-not-clinical-knowledge]] which may not exist in the current branch, and one existing claim adds a self-referential link in its related field, but these are expected cross-PR references that should not block approval.

5. Source quality: PMC12835689 is a peer-reviewed case report published in January 2026 in a PubMed Central indexed journal, providing credible clinical documentation appropriate for case-level evidence, though limited by n=1 generalizability.

6. Specificity: The new claim makes a falsifiable assertion that subclinical restrictive behaviors are "clinically invisible without structured assessment" and that screening is "required" for adolescent GLP-1 prescribing—someone could disagree by arguing clinical judgment alone is sufficient or that the 18-month undetected period reflects individual practitioner failure rather than systematic invisibility; all enriched claims maintain their original specificity with concrete mechanisms (developmental timing convergence, pre-existing substrate requirement, starvation spiral persistence post-discontinuation).

## Criterion-by-Criterion Evaluation **1. Schema:** All five modified claims contain valid frontmatter with type, domain, confidence, source, created, description, and title fields; the new claim `glp1-adolescent-prescribing-requires-eating-disorder-screening-because-subclinical-restriction-invisible-without-assessment.md` has complete schema with all required fields for a claim. **2. Duplicate/redundancy:** The PMC12835689 case evidence (18-month pre-prescription restrictive history, cardiac complications, rapid progression) is injected into five different claims, but each enrichment addresses a distinct aspect: developmental timing vulnerability, screening necessity, protocol recommendations, pre-existing substrate requirement, and starvation spiral mechanism—the evidence is appropriately reused to support different analytical angles rather than redundantly making the same point. **3. Confidence:** The new claim uses "experimental" confidence based on a single case report (PMC12835689), which is appropriately cautious; the existing claims retain their original confidence levels (experimental for developmental timing, experimental for screening protocol, low for GI side effects, speculative for starvation spiral), and the case evidence supports but does not strengthen these levels since it remains n=1 observational data. **4. Wiki links:** The new claim references `[[glp1-atypical-anorexia-screening-gap-creates-invisible-high-risk-population]]` and `[[glp1-eating-disorder-screening-gap-structural-capacity-not-clinical-knowledge]]` which may not exist in the current branch, and one existing claim adds a self-referential link in its related field, but these are expected cross-PR references that should not block approval. **5. Source quality:** PMC12835689 is a peer-reviewed case report published in January 2026 in a PubMed Central indexed journal, providing credible clinical documentation appropriate for case-level evidence, though limited by n=1 generalizability. **6. Specificity:** The new claim makes a falsifiable assertion that subclinical restrictive behaviors are "clinically invisible without structured assessment" and that screening is "required" for adolescent GLP-1 prescribing—someone could disagree by arguing clinical judgment alone is sufficient or that the 18-month undetected period reflects individual practitioner failure rather than systematic invisibility; all enriched claims maintain their original specificity with concrete mechanisms (developmental timing convergence, pre-existing substrate requirement, starvation spiral persistence post-discontinuation). <!-- VERDICT:LEO:APPROVE -->
leo approved these changes 2026-05-05 08:28:40 +00:00
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Approved.

Approved.
theseus approved these changes 2026-05-05 08:28:40 +00:00
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Approved.

Approved.
m3taversal commented 2026-05-05 08:29:11 +00:00
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Merged locally.
Merge SHA: 3adc221da7821fc6c02d0850f1a03bed98de7412
Branch: extract/2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case-8b04

Merged locally. Merge SHA: `3adc221da7821fc6c02d0850f1a03bed98de7412` Branch: `extract/2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case-8b04`
leo closed this pull request 2026-05-05 08:29:11 +00:00
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Reference: teleo/teleo-codex#10216
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