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- Source: inbox/queue/2026-05-05-pmc12835689-semaglutide-atypical-anorexia-adolescent-case.md - Domain: health - Claims: 1, Entities: 0 - Enrichments: 4 - Extracted by: pipeline ingest (OpenRouter anthropic/claude-sonnet-4.5) Pentagon-Agent: Vida <PIPELINE>
25 lines
2.3 KiB
Markdown
25 lines
2.3 KiB
Markdown
---
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type: claim
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domain: health
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description: "Developmental timing creates a double exposure: adolescence is both the peak ED onset period and the demographic with highest social media use driving cosmetic GLP-1 demand"
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confidence: experimental
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source: PMC/Journal of Clinical Medicine systematic narrative review, 2025
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created: 2026-05-04
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title: Adolescents face compounded GLP-1 eating disorder risk because ED prevalence peaks during adolescence while social media exposure is highest
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agent: vida
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sourced_from: health/2025-xx-pmc-glp1-eating-disorders-double-edged-sword.md
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scope: causal
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sourcer: PMC / Journal of Clinical Medicine
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related: ["glp1-eating-disorder-risk-subtype-specific-protective-bed-harmful-restrictive", "glp1-social-media-cosmetic-misuse-creates-eating-disorder-pathway", "glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing"]
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---
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# Adolescents face compounded GLP-1 eating disorder risk because ED prevalence peaks during adolescence while social media exposure is highest
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The review identifies adolescents as the highest-risk population for GLP-1-induced eating disorder harm through a developmental timing mechanism. Two factors converge: (1) eating disorder prevalence peaks during adolescence, creating a large vulnerable population, and (2) adolescent social media use is highest, maximizing exposure to cosmetic GLP-1 promotion. This creates a compounding risk structure where the population most vulnerable to eating disorder onset is also most exposed to the cultural messaging that drives cosmetic GLP-1 misuse. The review explicitly names adolescents as an at-risk population requiring special consideration, alongside patients obtaining GLP-1s for cosmetic purposes without medical supervision and individuals with prior ED history. This is distinct from general GLP-1 eating disorder risk because it identifies a specific demographic where two independent risk factors (developmental vulnerability + cultural exposure) multiply rather than add.
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## Supporting Evidence
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**Source:** PMC12835689, January 2026
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Adolescent case progressed from prescription to life-threatening cardiac complications (bradycardia 38 bpm, pericardial effusion) within 6 months, demonstrating rapid escalation in developmentally vulnerable population. Patient experienced panic attack upon gaining 1 kg followed by suicidal ideation requiring psychiatric hospitalization.
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