teleo/teleo-codex
8
1
Fork 0
Code Issues 22 Pull requests 1 Projects Releases Packages Wiki Activity Actions
teleo-codex/domains/health/glp1-eating-disorder-risk-doubles-with-prior-mental-health-history.md
Teleo Agents 9b7d1d4866 vida: extract claims from 2026-05-05-timmermanreport-dark-side-glp1-eating-disorders 
- Source: inbox/queue/2026-05-05-timmermanreport-dark-side-glp1-eating-disorders.md
- Domain: health
- Claims: 2, Entities: 0
- Enrichments: 2
- Extracted by: pipeline ingest (OpenRouter anthropic/claude-sonnet-4.5)

Pentagon-Agent: Vida <PIPELINE>
2026-05-05 04:29:34 +00:00

2.2 KiB
Raw Blame History

type domain description confidence source created title agent sourced_from scope sourcer supports related
claim health ISPOR study of 60,000+ GLP-1 users found those with prior mental health conditions had more than double the eating disorder incidence versus those without mental health history experimental ISPOR study via Timmerman Report, n=60,000+ GLP-1 users 2026-05-05 GLP-1 eating disorder risk doubles with prior mental health history creating identifiable high-risk population vida health/2026-05-05-timmermanreport-dark-side-glp1-eating-disorders.md correlational Luke Timmerman (Timmerman Report)
glp1-eating-disorder-screening-gap-structural-capacity-not-clinical-knowledge
glp1-discontinuation-predicted-by-psychiatric-comorbidity-creating-access-adherence-trap
glp1-eating-disorder-pharmacovigilance-signal-class-effect-obesity-population-specific
glp1-eating-disorder-screening-gap-structural-capacity-not-clinical-knowledge
glp1-psychiatric-effects-directionally-opposite-metabolic-versus-psychiatric-populations
glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing
glp1-eating-disorder-risk-subtype-specific-protective-bed-harmful-restrictive

GLP-1 eating disorder risk doubles with prior mental health history creating identifiable high-risk population

The ISPOR study analyzed over 60,000 GLP-1 users and found cumulative eating disorder incidence of 1.275% across all users, with a critical stratification: GLP-1 users with prior mental health conditions had MORE THAN DOUBLE the eating disorder risk compared to GLP-1 users without mental health history. This is a within-GLP-1-users comparison, not a comparison to non-GLP-1 controls, meaning the study identifies a behavioral substrate that predicts differential risk among those prescribed the medication. The finding establishes prior mental health history as the primary risk stratifier for GLP-1-associated eating disorders, creating an identifiable high-risk population. However, the study lacks a non-GLP-1 control group, so it cannot establish whether GLP-1 elevates absolute eating disorder risk above baseline in weight-management-seeking populations. The eating disorders were mainly anorexia nervosa diagnoses.