teleo-codex/domains/health/glp1-adolescent-eating-disorder-risk-amplified-by-developmental-timing.md

type	domain	description	confidence	source	created	title	agent	sourced_from	scope	sourcer	related
claim	health	Developmental timing creates a double exposure: adolescence is both the peak ED onset period and the demographic with highest social media use driving cosmetic GLP-1 demand	experimental	PMC/Journal of Clinical Medicine systematic narrative review, 2025	2026-05-04	Adolescents face compounded GLP-1 eating disorder risk because ED prevalence peaks during adolescence while social media exposure is highest	vida	health/2025-xx-pmc-glp1-eating-disorders-double-edged-sword.md	causal	PMC / Journal of Clinical Medicine	glp1-eating-disorder-risk-subtype-specific-protective-bed-harmful-restrictive glp1-social-media-cosmetic-misuse-creates-eating-disorder-pathway

Adolescents face compounded GLP-1 eating disorder risk because ED prevalence peaks during adolescence while social media exposure is highest

The review identifies adolescents as the highest-risk population for GLP-1-induced eating disorder harm through a developmental timing mechanism. Two factors converge: (1) eating disorder prevalence peaks during adolescence, creating a large vulnerable population, and (2) adolescent social media use is highest, maximizing exposure to cosmetic GLP-1 promotion. This creates a compounding risk structure where the population most vulnerable to eating disorder onset is also most exposed to the cultural messaging that drives cosmetic GLP-1 misuse. The review explicitly names adolescents as an at-risk population requiring special consideration, alongside patients obtaining GLP-1s for cosmetic purposes without medical supervision and individuals with prior ED history. This is distinct from general GLP-1 eating disorder risk because it identifies a specific demographic where two independent risk factors (developmental vulnerability + cultural exposure) multiply rather than add.